Professional Experience

2005 - 2018
(seit 2013 50%)

Senior Consultant for analyze & realize GmbH, Berlin

2004 - 2005

Teaching molecular genetics at “Gläsernes Labor”, Campus Berlin-Buch

Ausbildung

1992 - 1997

Graduate Study, doctoral research & Ph.D. at Cornell University, Ithaca, NY, USA

1989 - 1992

Study of Biology at Universität Hamburg; Vordiplom „very good“

1980-1989

High School Gymnasium Wentorf, near Hamburg, degree 1.3 GPA “very good”

Skills and Interests

Business Software

• Document management systems (Veeva, DataVision/ iEnvision)

• Data bank research (e.g. PubMed, DIMDI/AMIS, MedDRA)

• Literature database management(EndNote)

• Project management software -for reg. affairs management (JIRA)

• Agency software (TROI)

• Laboratory information management system/digital lab notebook (Labfolder)

• Sitely

Office Applications

• MS Office (Excel, Word, PowerPoint,Teams)

• Zoom

• Webex,

• SharePoint

• Adobe Photoshop

Norms and Regulations

• GxP (GMP, GDP, GCP, etc)

• ISO 9001

• 21 CFR Part 11

• EU Novel Food Regulation (EU) 2015/2283 (updated 2024)

• EMA & ICH guidelines

• OECD standards

Language skills

German (mother tongue), Englisch (business fluent), basic French and Latin

Personal interests

• Gardening

• Painting

• Voluntary work: Chair of Stiftung Kunstmuseum Moré (Moré Art Museum Foundation)

Publications (Numerous poster abstratcs & presentations not listed; * = corresponding author)

1.    Meckel, M, Ehrenberg, S, Schmidt, T., Ritt, P, Moré, MI, Bergmann, R, Mathe, D, Zhernosekov, K. (2025) Reduced renal uptake of various radiopharmaceuticals with sodium para-aminohippurate (PAH) coadministration in a rat model. J Nuclear Med 124.268411 https://doi.org/10.2967/jnumed.124.268411

2.    Böhm D, Volkmann M, Haag R, Moré MI, Schuricht K-U, Vöster J, More SD, Kohn B (2021) Behandlung feliner Hyperthyreose mit Thiamazol – Randomisierte kontrollierte multizentrische Studie zum Nachweis der Nichtunterlegenheit einer transdermalen Nanocarrier-Formulierung gegenüber der oralen Standardtherapie. Berliner und Münchner Tierärztliche Wochenschrift (134) 1-13.

3.    Papandreou, C, Moré, M,  and Bellamine, A (2020) Trimethylamine N-Oxide in relation to cardiometabolic health—cause or effect? Nutrients 12 (5), 1330, https://doi.org/10.3390/nu12051330

4.    Moré MI,Postrach E,Bothe G,Heinritz S, Uebelhack R (2020) A dose-escalation study demonstrates the safety and tolerability of cellobiose in healthy subjects. Nutrients 12 (1), 64,  https://doi.org/10.3390/nu12010064

5.    Gruendwald J, Uebelhack R, Moré MI* (2019) Rosa canina- Rose hip pharmacological ingredients and molecular mechanics counteracting osteoarthritis – a systematic review. Phytomedicine, 60, 152958: 1-10. https://doi.org/10.1016/j.phymed.2019.152958

6.    Gauruder-Burmester A, Heim S, Patz B, Seibt S. (Medical writing Moré MI) (2019) A Curcurbita pepo - Rhus aromatica - Humulus lupulus combination reduces overactive bladder symptoms in women – a noninterventional study. Planta Med 85(13): 1044-1053, https://doi.org/10.1055/a-0946-2280

7.    Moré MI* (2019) Saccharomyces boulardii CNCM I-745 — die medizinische Hefe verbessert die Funktion intestinaler Enzyme, MMW - Fortschritte der Medizin,161(4), 20-24, https://doi.org/10.1007/s15006-019-0290-5

8.    Heim S, Seibt S, Stier H and Moré MI*, (2018) Uromedic® pumpkin seed derived Δ7-sterols, extract and oil inhibit 5α-reductases and bind to androgen receptor in vitro. Pharmacology & Pharmacy , 9, 193-207. https://doi.org/10.4236/pp.2018.96015

9.    Moré MI*, and Vandenplas Y (2018) Saccharomyces boulardii CNCM I-745 improves intestinal enzyme function: A trophic effects review. Clinical Medicine Insights: Gastroenterology 11, 1–14, https://doi.org/10.1177/1179552217752679

10.    Brunken L, Piekarska M, Navarro L, Ashraf MI, Moré MI, Moré S (2017) Zulassung von Nanomaterialien vom Typ DendroSol. pharmind 79, Nr 11, 1539-1546. 

11.    Moré MI*, Gruenwald J, Pohl U, Uebelhack R. (2017)A Rosa canina - Urtica dioica - Harpagophytum procumbens/zeyheri combination significantly reduces gonarthritis symptoms in a randomized, placebo-controlled double-blind study.Planta Med. Jun 14. https://doi.org/10.1055/s-0043-112750

12.    Moré MI, Rutenberg D (2017) Soy lecithin-derived phosphatidylserine plus phosphatidic acid: effects on brain functions in elderly patients with Alzheimer’s disease and dementia. Aging Sci 5, 179. https://doi.org/10.4172/2329-8847.1000179

13.    Moré MI*, Swidsinski A. (2015) Saccharomyces boulardii unterstützt die Regenerierung der intestinalen Mikrobiota bei diarrhoeischen und antibiotischen Dysbiosen. MMW-Fortschritte der Medizin 157 (S6) 14-18.

14.    Moré MI*, Swidsinski A. (2015) Saccharomyces boulardii CNCM I-745 supports regeneration of the intestinal microbiota after diarrheic dysbiosis - a review. Clin Exp Gastroenterol. 11,237-55, https://doi.org/10.2147/CEG.S85574

15.    Moré MI*, Freitas U, Rutenberg D. (2014). Positive effects of soy lecithin-derived phosphatidylserine plus phosphatidic acid on memory, cognition, daily functioning, and mood in elderly patients with alzheimer’s disease and dementia. Advances in Therapy 31, 1247-1262.

16.    Moré MI*, Kenley D. (2014) safety and metabolism of aod9604, a novel nutraceutical ingredient for improved metabolic health. J Endocrinol Metab. 4, 64-77.

17.    Holz C, Alexander C, Balcke C, Moré MI, Auinger A, Bauer M, Junker L, Grünwald J, Lang C, Pompejus M. (2013) Lactobacillus paracasei DSMZ16671 reduces mutans streptococci: a short-term pilot study. Probiotics & Antimicro. Prot. 5, 259-263, https://doi.org/10.1007/s12602-013-9148-9

18.    Jüttner R, Moré MI, Das D, Babich A, Meier J, Henning M, Erdmann B, Müller E-C, Otto A, Grantyn R, and Rathjen FG. (2005) Impaired synapse function during postnatal development in the absence of CALEB, an EGF-like protein processed by neuronal activity. Neuron 46, 233-245.

19.    Erdmann B, Kirsch F-P, Rathjen FG, Moré MI*. (2003) N-Cadherin is essential for retinal lamination in the zebrafish. Dev. Dyn. 226, 570-577. 

20.    Schmidt H, Werner M, Heppenstall PA, Henning M, Moré MI, Kühbandner S, Lewin GR, Hofmann F, Feil R, Rathjen FG. (2002). cGMP-mediated signalling via cGKI alpha is required for the guidance and connectivity of sensory axons. J. Cell Biol. 159, 489-498.

21.    Moré MI, Kirsch F-P, Rathjen FG.  (2001). Targeted ablation of NrCAM or ankyrin-B results in disorganized lens fibres leading to cataract formation. J. Cell Biol. 154, 187-196.

22.    Paterson S, Moré MI, Pillay G, Cellini C, Woodgate R, Walker GC, Iyer VN, Winans SC.  (1999).  Genetic analysis of the mobilization and leading regions of the IncN plasmids pKM101 and pCU1. J. Bacteriol. 181, 2572-2583.

23.    J. Zhu, J. W. Beaber, Moré MI, C. Fuqua, A. Eberhard, S. C. Winans (1998).  Analogs of the autoinducer 3-oxooctanoyl-homoserine lactone strongly inhibit activity of the TraR protein of Agrobacterium tumefaciens. J. Bacteriol. 180,  5398-5405.

24.    Winans SC and Moré MI (1996).  Response to: The inner workings of a quorum sensing signal generator,  S. Swift, G. S. A. B. Stewart and P. Williams. TIM 4, 465-466.

25.    Moré MI, Finger LD, Stryker JL, Eberhard A, Fuqua C, Winans SC. (1996) Enzymatic synthesis of a quorum-sensing autoinducer through the use of defined substrates.  Science 272, 1655‑1658. 

26.    Moré MI, Pohlman RF, Winans SC (1996). Genes encoding the pKM101 mating pore are negatively regulated by the plasmid-encoded KorA and KorB proteins. J. Bacteriol. 178, 4392-4399.

27.    Silva MC, Moré MI, Batt CA (1995). Development of a molecular detection method for naphthalene degrading pseudomonads. FEMS Microbiol. Ecol. 18, 225-235.

28.    Moré MI, Herrick JB, Silva MC, Ghiorse WC, Madsen EL (1994). Quantitative cell lysis of indigenous microorganisms and rapid extraction of microbial DNA from sediment. Appl. Env. Microbiol. 60, 1572-1580.

29.    Pohlman RF, Liu F, Moré MI, Winans SC (1993). Genetic and biochemical analysis of an endonuclease encoded by the IncN plasmid pKM101. Nucl. Acid. Res. 21, 4867-4872.

Books/book Chapters

Moré MI , Libera M, Paulus F, Fleige E, Moré SD. (2018) Regulatory and risk assessment perspective for core-multishell nanocarriers: a novel excipient on its way towards marketing authorization. Chapter 4, in: Emerging Nanotechnologies in Immunology Elsevier, Shegokar, R, and Souto, EB (Eds). https://doi.org/10.1016/C2015-0-00098-3

Grünwald J and Jänicke C. Scientific support: Hardewig I, Köhler I, Freder J, Mönke-Liebig S, Moré MI. (2006) Alternativ heilen. Kompetenter Rat aus Wissenschaft und Praxis. GU Verlag.

Winans SC, Zhu J, and Moré MI (1999).  Cell density-dependent gene expression by Agrobacterium tumefaciens during colonization of crown gall tumors. in Cell-Cell Signaling in Bacteria.  G. M. Dunny,  and S. C. Winans (Eds).  ASM Press, Washington, D. C.

Winans SC, Wang L, Dwen P, Fuqua C, Moré MI, Alt-Mörbe J, Stryker J, Burbea M  (1996).  Transcriptional regulation of conjugal transfer genes of octopine-type Ti plasmids. pp. 59-74.  in Crown Gall: Advances in Understanding Interkingdom Gene Transfer.  W. Ream and S.B. Gelvin (Eds). American Phytopathology Society, St Paul.

Theses

Moré MI (1997) Regulation of conjugal transfer: Quorum dependent positive regulation of conjugation in Agrobacterium tumefaciens und negative regulation of conjugal operons by KorA und KorB of the IncN plasmid pKM101 in E. coli. Ph. D. Thesis, Cornell University, Section of Microbiology.

Finger LD, Moré MI, Eberhard A, Winans SC. (1996) A novel synthetic method for the preparation of 3-oxoacylcoenzyme A and acyl carrier protein derivatives. B. S. Honors Thesis, Ithaca College, Department of Chemistry.